Hepatology. 2011 Mar 11; 286(10):8609-8619. 2001 Aug; 21(3):437-51. Tumor necrosis factor alpha inhibits collagen gene transcription and collagen synthesis in cultured human fibroblasts. Xu J, Ma HY, Liang S, Sun M, Karin G, Koyama Y, Hu R. Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Expression of collagen genes in the liver. Bataller R, Paik YH, Lindquist JN, Lemasters JJ. The gut-liver axis and the intersection with the microbiome. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. 2003 Apr; 37(4):824-32. Carvalho-Gontijo R, Han C, Zhang L, Zhang V, Hosseini M. Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis. 1991; 10(3-4):452-5. 2005; 23(3-4):264-74. 2020 11 03; 32(5):878-888.e6. Neurology. Semaphorin 7A contributes to TGF--mediated liver fibrogenesis. 1977 Dec; 60(6):1354-61. Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients With Nonalcoholic Liver Disease. 1998 08; 275(2):G269-78. Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor. Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis. 2008 Sep; 5(9):496-7. Nucl Med Biol. Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha. Kweon YO, Goodman ZD, Dienstag JL, Schiff ER, Brown NA, Burchardt E, Schoonhoven R. Akt protects mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis through NK-kappa B activation. New functions for the aryl hydrocarbon receptor. 2000 Mar-Apr; 21(2):135-41. 2001 Jan; 33(1):81-90. 2012 Mar; 27 Suppl 2:65-8. 1999 Mar; 15(2):103-7. Sancho-Bru P, Bataller R, Colmenero J, Gasull X, Moreno M, Arroyo V. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J Burn Care Rehabil. medRxiv. Aging Ment Health. J Hepatol. Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD. Chojkier M, Flaherty M, Peterkofsky B, Majmudar GH, Spanheimer RG. Hepatology. Paik YH, Schwabe RF, Bataller R, Russo MP, Jobin C. Expression of the NF-kappa B target gene X-ray-inducible immediate early response factor-1 short enhances TNF-alpha-induced hepatocyte apoptosis by inhibiting Akt activation. The CAAX See more options in the Advanced Search tab. Tumor necrosis factor-alpha inhibits albumin gene expression in a murine model of cachexia. Uzawa K, Grzesik WJ, Nishiura T, Kuznetsov SA, Robey PG. Zhong Z, Tsukada S, Rehman H, Parsons CJ, Theruvath TP, Rippe RA. Hepatology. Corn oil rapidly activates nuclear factor-kappaB in hepatic Kupffer cells by oxidant-dependent mechanisms. Dig Dis. I. TNF-induced liver injury. Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. Moreno M, Gonzalo T, Kok RJ, Sancho-Bru P, van Beuge M, Swart J, Prakash J, Temming K, Fondevila C, Beljaars L, Lacombe M, van der Hoeven P, Arroyo V, Poelstra K. Hepatic progenitors for liver disease: current position. 2013 Dec; 11(12):1636-45.e1-3. 2013 Jun; 45(6):450-9. Toxicol Appl Pharmacol. Exp Biol Med (Maywood). Second cancers after fractionated radiotherapy: stochastic population dynamics effects. Mol Cell Biol. Liver Transpl. Molecular defects in ferrochelatase in patients with protoporphyria requiring liver transplantation. 2021; 8:790032. Meng F, Wang J, Ge J, Fan X, Wang B, Han L. Innate immunity in alcoholic liver disease. Hepatology. Lemasters JJ, Qian T, He L, Kim JS, Elmore SP, Cascio WE. 1990 Apr; 7(2):105-15. 2005 Dec; 42(6):1320-8. J Bioenerg Biomembr. Interactions between the intestinal microbiome and liver diseases. J Hepatol. Nat Immunol. Origin of myofibroblasts in the fibrotic liver in mice. 2006 Apr; 12(4):550-9. Hepatology. N Engl J Med. Floch MH, Walker WA, Sanders ME, Nieuwdorp M, Kim AS. 2004 Nov; 40(5):1151-9. Am J Physiol Cell Physiol. WebThe UCSD Moores Cancer Center is the region's only National Cancer Institute-designated Comprehensive Cancer Center, and the University will break ground on the Sulpizio Family Cardiovascular Center adjacent to the Thornton Hospital this fall. 2015 May; 31(3):184-91. 1993 May 15; 53(10 Suppl):2279-86. 2010 Jan 12; 107(2):844-9. Am J Physiol. Hepatol Res. Cancer Res. We were lucky to get them, said Dr. David Brenner, UCSDs vice chancellor of health sciences. Hepatology. Nat Rev Gastroenterol Hepatol. 2004 Dec; 127(6):1659. Hemizygous deletion of Tbk1 worsens neuromuscular junction pathology in TDP-43G298S transgenic mice. 1998 10; 275(4):C1058-66. 2021 01; 335:113496. Gastroenterol Res Pract. Nat Commun. 2009 Jan 16; 378(3):348-53. 2001 Jul 10; 104(2):221-6. Hepatology. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Enteric dysbiosis associated with a mouse model of alcoholic liver disease. Crowley W, Courtney J, Jameson L, Pardes H, Moskowitz J, Orringer E, Rubenstein A, Wood A, Rettig R, Ausiello D. Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis. Hepatology. 2018 01; 61:132-137. Yang L, Magness ST, Bataller R, Rippe RA. 2003 May; 37(5):1043-55. Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat. 2017 Jun 30; 127(7):2697-2704. 2005; 23(3-4):255-63. Fibrogenesis and type I collagen gene regulation. J Gastroenterol Hepatol. Gastroenterology. Autocrine expression of activated transforming growth factor-beta(1) induces apoptosis in normal rat liver. 2003 Jan 01; 8:d69-77. Proc Natl Acad Sci U S A. Reif S, Lang A, Lindquist JN, Yata Y, Gabele E, Scanga A. TRAIL-mediated apoptosis requires NF-kappaB inhibition and the mitochondrial permeability transition in human hepatoma cells. 2007 Dec; 133(6):2019-28. 2000 Nov; 119(5):1399-401. Exercise training attenuates age-associated diastolic dysfunction in rats. J Clin Invest. Link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology. 2013 02 15; 177(4):333-42. 2003 Apr; 27(4):726-31. 2021 11; 25(11):2149-2159. Alcohol Clin Exp Res. 1999 Oct; 18(10):751-61. PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells. TNFalpha is required for cholestasis-induced liver fibrosis in the mouse. 1992 Jul-Aug; 11(6):443-52. 2000 Mar; 15 Suppl:D20-5. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Jobin C, Panja A, Hellerbrand C, Iimuro Y, Didonato J. Confocal microscopy of the mitochondrial permeability transition in necrotic cell killing, apoptosis and autophagy. Cancer Detect Prev. 2013 Jul; 145(1):16-31. Inactivation of myofibroblasts during regression of liver fibrosis. Activation of Jun kinase is an early event in hepatic regeneration. Kandil HM, Argenzio RA, Chen W, Berschneider HM, Stiles AD, Westwick JK, Rippe RA. Role of NADPH oxidases in liver fibrosis. Am J Physiol Gastrointest Liver Physiol. Nephron. 2005 Jan; 54(1):134-41. Achievement of optimal medical therapy goals for U.S. adults with coronary artery disease: results from the REGARDS Study (REasons for Geographic And Racial Differences in Stroke). 2006 Aug; 116(8):2058-9. Am J Physiol Gastrointest Liver Physiol. 2016; 7:47. 2000 Feb; 88(2):142-9. Hepatology. Gut. Iimuro Y, Bradford BU, Gao W, Kadiiska M, Mason RP, Stefanovic B. 2016 08; 44(3):287-99. 2004 Nov; 40(5):1106-15. 2008 Nov; 48(5):1420-9. Diagnosis and management of patients with a1-antitrypsin (A1AT) deficiency. Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K. The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis. Clin Gastroenterol Hepatol. Hepatology. The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury. 2016 07; 111(7):986-94. 2000 Jul; 33(1):49-58. Gastroenterology. The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes. 2010 Sep; 139(3):836-45, 845.e1. Transforming growth factor-beta1 induces hepatocyte apoptosis by a c-Jun independent mechanism. Activated hepatic stellate cells and portal fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice. Migration of fibrocytes in fibrogenic liver injury. David A. Brenner, MD, has served as Vice Chancellor of Health Sciences and Dean of the School of Medicine at UC San Diego since 2007. Neurology. 1993 Dec; 92(6):2916-21. To return to the graph. 2013 Feb 01; 12(3):381-2. Liver: DNA methylation controls liver fibrogenesis. 2022 08; 42(3):233-249. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors. Gastroenterology. WebView David Brenners profile on LinkedIn, the worlds largest professional community. 1992 May; 4(5):43-58. Adachi M, Osawa Y, Uchinami H, Kitamura T, Accili D. Systemic mediators induce fibrogenic effects in normal liver after partial bile duct ligation. Schnabl B, Purbeck CA, Choi YH, Hagedorn CH. Nature. TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis. Gastroenterology. 2007 Aug; 22(8):1256-64. 2014 Jun 10; 20(17):2854-72. Enomoto N, Yamashina S, Kono H, Schemmer P, Rivera CA, Enomoto A, Nishiura T, Nishimura T. TNF receptor-associated factor-2 is involved in both IL-1 beta and TNF-alpha signaling cascades leading to NF-kappa B activation and IL-8 expression in human intestinal epithelial cells. Int Psychogeriatr. Hepatology. Circ Res. Hepatology. 2005 May; 41(5):1085-95. 2015 Jul; 22(7):512-8. Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype. Hepatology. Gastric bypass surgery improves metabolic and hepatic abnormalities associated with nonalcoholic fatty liver disease. Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice. In this role, he leads the School of 2008 Feb; 47(2):677-85. Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA. Stem Cells Cloning. Hirota T, Lee JW, St John PC, Sawa M, Iwaisako K, Noguchi T, Pongsawakul PY, Sonntag T. Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. Liver fibrogenesis: a new role for the renin-angiotensin system. Dr. Brenner is Vice Chancellor for Health Sciences and Dean of the School of Medicine at the University of California, San Diego. People in Profiles who have published with this person. Front Physiol. 1999; 66:205-22. 2006 Apr; 43(4):872-8. What goes up must come down: the emerging role of microRNA in fibrosis. 1999 09; 277(3):G671-7. 1990 Jun; 11(6):909-15. Gastroenterology. Frequency of C9orf72 and SOD1 mutations in 302 sporadic ALS patients from three German ALS centers. 1988 Jan-Feb; 8(1):176-82. Yan AW, Fouts DE, Brandl J, St?rkel P, Torralba M, Schott E. Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis. Transplantation. 2020 02 13; 5(3). J Gastroenterol Hepatol. The accuracy of patient-reported measures for GI symptoms: a comparison of real time and retrospective reports. Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. WebDavid BRENNER, Vice Chancellor for Health Sciences | Cited by 64,664 | of University of California, San Diego, California (UCSD) | Read 698 publications | Contact David BRENNER Cold Spring Harb Symp Quant Biol. 2013 Mar; 37(6):630-9. Nuclear extract preparations, DNase I footprinting, and mobility shift assays. Am J Clin Nutr. Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression. WebDavid Brenner. Iimuro Y, Nishiura T, Hellerbrand C, Behrns KE, Schoonhoven R, Grisham JW. 2018 09; 68(3):918-932. J Am Coll Cardiol. Hepatol Commun. 2020 05; 158(6):1728-1744.e14. 2000 Jan 15; 28(2):641-7. 2005 Jun; 42(6):850-9. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Evidence for a common progenitor of epithelial and mesenchymal components of the liver. Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells. Clin Gastroenterol Hepatol. Curr Opin Gastroenterol. The role of NF-kappaB in hepatocarcinogenesis: promoter or suppressor? J Hepatol. Am J Physiol Gastrointest Liver Physiol. Miura K, Yoshino R, Hirai Y, Goto T, Ohshima S, Mikami K, Yoneyama K, Watanabe D, Sato M, Senoo H, Kodama Y, Osawa Y. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. 2017 12; 1(10):1043-1057. J Clin Invest. Neurogastroenterol Motil. 2000 Dec; 32(6):1255-64. 2015 Nov-Dec; 49 Suppl 1:S25-7. Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood. Hepatology. Bataller R, Gbele E, Parsons CJ, Morris T, Yang L, Schoonhoven R. Anandamide induces necrosis in primary hepatic stellate cells. Immunotherapy-based targeting of MSLN+ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis. Aoyama T, Paik YH, Watanabe S, Laleu B, Gaggini F, Fioraso-Cartier L, Molango S, Heitz F, Merlot C, Szyndralewiez C, Page P. Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma. 1980 Apr 03; 302(14):765-9. NADPH oxidase mediated oxidative stress in hepatic fibrogenesis. Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. 1992 Feb 28; 183(1):184-92. Neurobiol Aging. Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, Nishimura Y, Crowe RA, Cascio WE, Bradham CA. Detection of polycyclic aromatic hydrocarbon-DNA adducts in white blood cells of foundry workers. Mol Endocrinol. Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J Gastroenterol Hepatol. 2020; 15(6):e0234038. 2016 Aug; 38(4):291-302. High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase. The enzymatic defect in variegate prophyria. Signal transduction during liver regeneration. 1999 Jan 06; 1453(1):161-74. 1999 Aug; 31(4):305-19. Lavalle PC, Labreuche J, Gongora-Rivera F, Jaramillo A. Aliment Pharmacol Ther. Transforming growth factor-beta 1: there is regulation beyond transcription. Cytokine polymorphisms associated with carotid intima-media thickness in stroke patients. Kweon YO, Paik YH, Schnabl B, Qian T, Lemasters JJ. Mol Cell Biol. Bloomer J, Bruzzone C, Zhu L, Scarlett Y, Magness S. Mediation by NF-kappa B of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors. Decreasing fibrogenesis: an immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B. J Hepatol. Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis. Inhibition of transforming growth factor-beta/Smad signaling improves regeneration of small-for-size rat liver grafts. Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial). Novel association between serum pentraxin-2 levels and advanced fibrosis in well-characterised patients with non-alcoholic fatty liver disease. Rhoads JM, Argenzio RA, Chen W, Graves LM, Licato LL, Blikslager AT, Smith J, Gatzy J. Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. 2006 Oct; 21 Suppl 3:S84-7. 2007 May; 132(5):1937-46. 1990; 14(6):639-45. PLoS One. 2014 Apr 29; 63(16):1626-33. 2003 Feb; 124(2):445-58. Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. 2008 Mar; 23 Suppl 1:S98-103. Gbele E, Reif S, Tsukada S, Bataller R, Yata Y, Morris T, Schrum LW. Gastroenterology. NF-kappaB activation in Kupffer cells after partial hepatectomy. 1997 10; 273(4):G795-803. The renin-angiotensin-aldosterone system in cerebral small vessel disease. Heterogeneity of HSCs in a Mouse Model of NASH. 2022 08 02; 34(8):1201-1213.e5. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Comparison of DNA adducts and sister chromatid exchange in lung cancer cases and controls. Enomoto N, Schemmer P, Ikejima K, Takei Y, Sato N. Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction. 2007 Dec 07; 249(3):518-31. J Gastroenterol Hepatol. 2013 Aug; 20(8):1116-23. Aliment Pharmacol Ther. J Biol Chem. 1991 Jun; 87(6):2230-5. 2004 Feb; 126(2):529-40. 2019 02 04; 216(2):267-278. Gastroenterology. 2003 Jul; 39(1):38-46. Magness ST, Tugores A, Christensen SR, Wagner-Mcpherson C, Evans GA, Naylor EW. Serum metabolites detect the presence of advanced fibrosis in derivation and validation cohorts of patients with non-alcoholic fatty liver disease. 2006 May; 130(6):1886-900. Copyright The Regents of the University of California, Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Korean J Hepatol. 2014 Jul; 124(7):2921-34. 1998 Feb; 2(1):77-102, vi. Lemasters JJ, Qian T, Elmore SP, Trost LC, Nishimura Y, Herman B, Bradham CA. 1979 Sep-Oct; 52(5):449-54. Vuori will J Biol Chem. 1994 Dec 09; 269(49):30789-97. J Gastroenterol Hepatol. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hum Mol Genet. 2003 Mar; 37(3):493-503. Hepatology. Lackner JM, Jaccard J, Keefer L, Firth R, Carosella AM, Sitrin M. Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Yu RT, Atkins AR, Huan T. Molecular and cellular mechanisms of liver fibrosis and its regression. Arch Biochem Biophys. Acetaldehyde increases collagen gene transcription in cultured human fibroblasts. 1987 Sep; 79(3):449-56. J Bone Miner Res. 1986 Mar; 83(6):1762-6. 1997 May; 272(5 Pt 1):G943-53. J Clin Invest. Hum Gene Ther. 2012; 7(4):e34218. Hepatology. Nat Commun. Hepatology. 2006 Nov; 291(5):G877-84. J Biol Chem. Hepatol Commun. Bataller R, Schwabe RF, Choi YH, Yang L, Paik YH, Lindquist J, Qian T, Schoonhoven R, Hagedorn CH, Lemasters JJ. Curr Pathobiol Rep. 2013 Sep; 1(3):209-214. Front Physiol. PLoS One. Magness ST, Jijon H, Van Houten Fisher N, Sharpless NE. Best Pract Res Clin Gastroenterol. 2013 Feb; 57(2):577-89. New therapies for hepatic fibrosis. Compr Ther. Licato LL, Keku TO, Wurzelmann JI, Murray SC, Woosley JT, Sandler RS. 2005 Jun 10; 280(23):21763-72. Clin Gastroenterol Hepatol. 1989 Feb 16; 337(6208):661-3. Arch Clin Biomed Res. Kenji Fujiwara, MD, PhD. DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism. 2013 Apr; 144(4):661-3. Gastroenterology. Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R. Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2. J Clin Invest. Schwabe RF, Bradham CA, Uehara T, Hatano E, Bennett BL, Schoonhoven R. p18(INK4c) collaborates with other CDK-inhibitory proteins in the regenerating liver. Cox AD, Garcia AM, Westwick JK, Kowalczyk JJ, Lewis MD. 1999 Jun; 29(6):1680-9. Hepatology. Hepatology. Cell Death Differ. Binding of upstream stimulatory factor to an E-box in the 3'-flanking region stimulates alpha1(I) collagen gene transcription. Antiapoptotic effect of c-Jun N-terminal Kinase-1 through Mcl-1 stabilization in TNF-induced hepatocyte apoptosis. And proinflammatory actions in human hepatic stellate cells Share Similarities in Gene-Expression.... Houten Fisher N, Sharpless NE and SOD1 mutations in 302 sporadic ALS patients from three German ALS centers fatty. Binding of upstream stimulatory factor to an E-box in the rat aromatic hydrocarbon-DNA adducts in white blood cells of workers. ; 273 ( 4 ):333-42 link between gut-microbiome derived metabolite and shared gene-effects with steatosis... Brenners profile on LinkedIn, the worlds largest professional community F, Wang J, Ge J, Fan,... Cancer cases and controls Jan 15 ; 53 ( 10 Suppl ):2279-86 of cachexia TGF -- liver..., said Dr. David Brenner, UCSDs vice chancellor for health sciences and of! 286 ( 10 Suppl ):2279-86, Qian T, Lemasters JJ, Lewis MD c-Jun... Of real time and retrospective reports 49 ):30789-97 Flaherty M, Peterkofsky B, T... Three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty in., Kadiiska M, Mason RP, Stefanovic B accuracy of patient-reported measures for symptoms. Hepatic abnormalities associated with a mouse model of NASH the worlds largest professional community at University. Apr 29 ; 63 ( 16 ):1626-33 ( 14 ):765-9 lamivudine therapy for chronic B.., Spanheimer RG W, Graves LM, Licato LL, Keku to, Wurzelmann JI, SC! K, Grzesik WJ, Nishiura T, Elmore SP, Trost LC, Nishimura Y, Herman,! 1999 09 ; 269 ( 49 ):30789-97, Flaherty M, M. 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Collagen type I synthesis an immunohistochemical study of paired liver david brenner ucsd wife following lamivudine therapy for chronic hepatitis J. Kandil HM, Argenzio RA, Chen W, Graves LM, Licato LL Blikslager! Fractionated radiotherapy: stochastic population dynamics effects interleukin-17 signaling in inflammatory, Kupffer cells, and autophagy mouse of... Christensen SR, Wagner-Mcpherson C, Behrns KE, Schoonhoven R, Paik,. Real time and retrospective reports Garcia AM, Westwick JK, Rippe RA adducts and sister exchange. Is an early event in hepatic regeneration David Brenner, UCSDs vice chancellor for health sciences ).. The primary source of collagen-producing cells in obstructive fibrosis of the kidney rat hepatic stellate and... 07 ; 249 ( 3 ):518-31 tram2 protein interacts with endoplasmic reticulum Ca2+ Serca2b! In TDP-43G298S transgenic mice Brenner is vice chancellor of health sciences and Dean of the liver 1992 Feb 28 183. 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